Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer
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GBC
ON LINE FIRST: 15 JANUARY 2013
 
EDITORIAL
Statins for reducing cancer death risk? Molecular evidence vs. statistics
A study published recently in NEJM, which was based on the network of national databases in Denmark, reveals an antitumor effect of statins in preventing cancer. Is that true?
 
NEWS & VIEWS
 
GBC
CURRENT ISSUE: 2012, (Oct)Vol. 11, Issue 4, pages 196-241
 
PERSPECTIVE

Innovative drug targets: Cooperative DNA, RNA and proteins networks.
High-throughput sequencing and arrays platforms provide now a global clinical genomic landscape. Computational predictive models can provide molecular networks-based identification of drug targets and prediction of therapeutic response by using signaling pathways network, PPI and gene-gene interactions analysis.

Improving survival with trastuzumab emtansine for HER2-positive breast cancer.
In patients with HER2-posutive breast cancer subtype, trastuzumab emtansine (T-DM1) as compared with lapatinib plus capecitabine in a phase 3 randomized trial, has improved survival. Can T-DM1 become a new standard treatment?

Trametinib plus dabrafenib : Targeting RAS-MAPK pathway for BRAF V600-mutant melanoma.

 
EDITORIAL

Adding Fulvestrant to Anastrozole prolongs survival in Breast Cancer.

Cellular signaling networks exploration for clinical applications.
Understanding and predicting signaling pathways is a top research priority by pharmaceutical industry and academia. However, much more work is needed to establish robust predictive dynamics of networks.
Healthy longevity: Approaching life mystery in genome science era.
Despite advances, the achievement of healthy longevity remains an unresolved problem. In the era of genome science, network biology and clinical genome, what are the challenges to be overcome?
 
NEWS & VIEWS

Tyrosine kinase inhibitors expand indications for surgical resection of advanced GIST.

Advances and limitations with multimodal treatment of Colorectal cancer liver metastases.

GBC
PAST ISSUE
PERSPECTIVE
 

Cancer single pathways inhibitors: More resistance than durable success in the clinic

 
 
EDITORIAL
 
 
 
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REVIEW
 

Predictive molecular tools to personalized gastric cancer  targeted therapy.

GENOMIC NETWORK MEDICINE

BREAST CANCER
GENOME OUTLOOK

Online ISSN : 1109 - 7647
Print ISSN : 1109 - 7655 ..

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last update: 22 January 2013