Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer


Figure 5 | Receptor tyrosine kinases:sites of therapeutic intervention. Deregulation of the receptor tyrosine kinase (RTK) signalling network is crucial for the development and progression of hyperproliferative diseases as cancer. Neutralizing antibodies, which block the bioactivity of RTK ligands, RTK-targeted antibodies, which either target overexpressed receptors or receptor heterodimerization, and small-molecule inhibitors RTK kinase activity have been developed to interfere with RTK signal transduction.

Online ISSN : 1109 - 7647
Print ISSN : 1109 - 7655
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last update: 3 February 2004