Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2012.0238

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Preoperative chemoradiotherapy for rectal cancer: Why revision and concerns are now shaped?

Franco Roviello, MD

Affiliation: Professor Franco Roviello, Via A. De Gasperi, 5-53100 Siena, Italy

E-mail : roviello@unisi.it

Since there is no abstract available we provide the first paragraph.
Over the past decade, neoadjuvant chemoradiotherapy has established as the standard approach for selected patients with advanced non-metastatic rectal cancer. But now meta-analyses, analysing data from more recent phase 3 randomized controlled trials raise a series of question and uncertainty about benefit-risk analysis neoadjuvant treatment. Given that this information is important not only for surgeons and oncologists but also patients, we describe benefits and complications of neoadjuvant treatment in a lack of robust biomarkers to predict who patients really respond and benefit from the preoperative chemoradiotherapy.

(Citation: Gastric & Breast Cancer 2012; 11(3): 154-156).

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Online ISSN : 1109 - 7647
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last update: 10 July 2012