Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2011.0166


Genotyping vs. exome sequencing for cancer.

Dr. John Spiliotis, M.D.

Affiliation: Dr. John Spiliotis, Head of Department of Surgery, "METAXA" Cancer Memorial Hospital, Botosi 51, TK 18535, Piraeus, Greece.


Since there is no abstract available we provide the first paragraph.

The advent of next-generation sequencing (NGS) with the powerful unprecedented ability for the whole genome scan or exome sequencing –sequence of all the coding regions of our genome- allows the unbiased identification of mutations involved in various cancer types [1-5]. Traditional genotyping of individual genes has also been widely evaluated and may provide useful information for the clinic. A recent example of gastric cancer genotyping has been recently published [6]. Here it is evaluated the potential utility and challenges of traditional genotyping.

(Citation: Gastric & Breast Cancer 2011; 10(2): 103-105)



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last update: 16 March 2011