Current best practices and rationalistic perspectives in causation-based prevention, early detection and multidisciplinary treatment of breast and gastric cancer

Gastric & Breast Cancer e-journal
DOI: 10.2122/gbc.2011.0166

NEWS & VIEWS

Genotyping vs. exome sequencing for cancer.

Dr. John Spiliotis, M.D.

Affiliation: Dr. John Spiliotis, Head of Department of Surgery, "METAXA" Cancer Memorial Hospital, Botosi 51, TK 18535, Piraeus, Greece.

E-mail: jspil@in.gr

Since there is no abstract available we provide the first paragraph.

The advent of next-generation sequencing (NGS) with the powerful unprecedented ability for the whole genome scan or exome sequencing –sequence of all the coding regions of our genome- allows the unbiased identification of mutations involved in various cancer types [1-5]. Traditional genotyping of individual genes has also been widely evaluated and may provide useful information for the clinic. A recent example of gastric cancer genotyping has been recently published [6]. Here it is evaluated the potential utility and challenges of traditional genotyping.

(Citation: Gastric & Breast Cancer 2011; 10(2): 103-105)

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last update: 16 March 2011