Does the trend and efforts towards a steadily increasing number
of patients who treated with a less extensive surgery, by expanding
the eligibility criteria, increase the risk of close or positive
(b) what is the effect of microscopic evidence
of close or positive margin on the risk of IBTR
(c) should the women with a final close or positive
resection margin undergone further surgery or a re-excision can
be avoided by the availability of current effective adjuvant treatment
-radiation, chemotherapy, tamoxifen-?
(d) Is local failure a true recurrence or a new
primary ipsilateral breast tumor?