Current
best practices and rationalistic perspectives in causation-based
prevention, early detection and multidisciplinary treatment
of breast and gastric cancer
|
Quality
of surgery
|
Tumor Stage-Based Tailored Therapeutic Strategy: Rational Approach or New Trend?  GBC-Editor’s Lecture in 5th IGCC, Rome May 4-7, 2003 Fruits and vegetables: Do they protect from gastric cancer? Extensive version of this our own work in Gastroenterology Journal
Time
to move on from current strategy?
Clinical management:
|
Conventional staging imperfectly predicts recurrence and survival in some patients. New biologic markers may be the answer
10- & 20-years follow-up results from randomized controlled trials (RCTs) comparing breast-conserving treatment with total mastectomy establish:
 Lack of generalizability of randomized trials to individuals suggests that although most women benefited from breast conservation in some others mastectomy is more beneficial.
5-20% depended on risk factors -young age, final margin status, EIC and treatment (surgery, radiation, chemotherapy, tamoxifen).
10-48%! is the rate of close or PRM and 9-54%! of these patients develop local recurrence.
|
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
NEW
data - Perspectives, Clinical Implications
